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Manufacturers of generic drugs cannot use brand names on their pharmaceuticals as that would be the breach of copyright while using the well known ingredients is absolutely legal.
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A generic drug manufacturer spends less money on product development and advertising.




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The most common reasons for exclusion from the study were the absence of documentation of epoetin-associated antibodies (208 cases), the use of multiple epoetin products (44 cases), duplicate reports (34 cases), and features inconsistent with the diagnosis of pure red-cell aplasia (29 cases).

One of Amgen's competitors, Genetics Institute (GI), was the first to isolate a purified strain of the protein and had received a patent on natural, highly purified EPO.

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In clinical studies of CKD patients on dialysis, Epogen increased hemoglobin levels and decreased the need for RBC transfusion.

Arteriovenous ( AV) Fistula A blood vessel that is made by surgically sewing together an artery and a vein (often in the forearm) to create the rapid blood flow from the heart needed for efficient hemodialysis.

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All patients are seeing the copay at this particular stage because the product is not properly on formulary yet as being too high a copay, and they abandon the prescription and they walk away.

FDA News Release: FDA modifies dosing recommendations for Erythropoiesis-Stimulating Agents.

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The language buried in Section 632 ofdelays a set of price restraints on a class of drugs that includes Sensipar, a lucrative Amgen pill used by kidney dialysis patients.

Epoetin alfa (Epogen, Procrit) and darbepoetin alfa (Aranesp) are erythropoietin-stimulating agents that can help boost the red blood cell count of some bone marrow failure patients.

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The drug treatment, which is given or by injection, is expensive and its stimulation of the bone marrow lasts only a few hours.

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The goals of this therapeutic guideline policy is to promote overall disease management such that medication treatment is supported by adjunctive psychosocial programs, ample patient contact, and frequent follow-up visits throughout the course of therapy to address non-medication treatment alternatives, comorbid disorders, dosage titration, adverse effects, and drug diversion and misuse.

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Jake, before you go on to the next question, Tony had an additional comment on Geoff Meacham's question about the Repatha demand indicators.

Only take important medicine, for example, those used for epilepsy, blood pressure, pain, heartbeat rhythm, asthma, migraines, and diabetes.

A generic drug is usually called by the name of the active ingredient while a manufacturer uses a brand name.

This is easily explained by a number of marketing and production differences.

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Do not use Epogen from multi-dose vials in newborns, infants, pregnant or breastfeeding women because the Epogen in these vials contains benzyl alcohol.

Desensitization: Process by which a person who has a history of allergic reaction to a drug has it slowly introduced into their bloodstream over time in such a way that the reaction does not occur.

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